Prostate Plus

A Multi-System Approach to Prostate Health

This formula is designed specifically to support healthy prostate function however there are some other multi-system benefits as well.

It tackles benign prostatic enlargement (BPE/BPH) through multiple mechanisms including hormonal balance, inflammation reduction, oxidative stress control, smooth muscle relaxation, and cellular health, offering broad and effective relief. These same mechanisms can help with other health factors we will discuss below.

This blend is carefully crafted to address crucial aspects of men's health:

• Hormonal balance (DHT/testosterone)

• Inflammation & oxidative stress

• Cellular proliferation, apoptosis & tissue structure

• Smooth muscle tone & urinary flow

• Metabolic, cardiovascular & anti-aging support

1. Serenoa repens (Saw Palmetto)

• 5α-reductase inhibition: Reduces conversion of testosterone to DHT, a key driver in BPH development.

• Urinary symptom relief: Demonstrates similar efficacy to finasteride in improving urinary flow with fewer side effects

• Marginal benefit alone: However, meta-analyses suggest limited impact when used in isolation, with better outcomes in combination formulations. Which is exactly why we use this wonderful herb in combination to address those underlying factors contributing to prostate health.

• Libido and sexual health: Offers anti-inflammatory and antioxidant effects without adverse impacts on libido or sexual function

2. Urtica dioica (Stinging Nettle)

• Inhibits DHT binding and moderates sex-hormone–binding activity.

• Reduces prostate inflammation and stromal/epithelial proliferation.

• Clinically proven to lower IPSS/PSA and reduce prostate volume.

3. Centella asiatica (Gotu Kola)

• Suppresses androgen receptors and PI3K/Akt pathway, both implicated in prostate enlargement.

• Supports prostate tissue integrity by regulating cell proliferation.

• Supports healthy brain function and improves circulation.

4. Hibiscus sabdariffa

• Blocks NF-κB, Akt, MMP pathways, reducing inflammation and preventing tissue degeneration.

Prostate Health:
Calms inflammation and guards prostate tissue integrity.

Cardiovascular Health:
Lowers blood pressure and eases artery stress—especially valuable for men balancing prostate and heart wellness.

Metabolic & Anti-Aging Support:
With anti-inflammatory and antioxidant actions, it contributes to metabolic balance and aging resilience.

5. Punica granatum (Pomegranate)

• Rich in polyphenols that stimulate apoptosis and block MMP-driven cell migration.

• Improves antioxidant defenses, lowering oxidative stress implicated in both BPH and prostate cancer.

• Clinical trials show slowed PSA doubling in specific genetic subgroups and overall prostate support in active surveillance scenarios.

6. Vitis vinifera Seed (Grape Seed Extract)

• Packed with proanthocyanidins—powerful antioxidants that inhibit inflammation and proliferation.

• Anti-angiogenic, pro-apoptotic activity; early trials show slowed PSA progression and tumor growth in prostate cancer contexts.

7. Turmeric (Curcuma longa, Curcumin)

• BPH pathways: Reduces inflammation, oxidative stress, growth factors (VEGF, IGF-1, TGF-β1), and suppresses androgen signaling.

• Metabolic syndrome & cardiovascular health: Improves fasting glucose, triglycerides, LDL, HDL, diastolic BP, and even waist circumference in overweight and hypertensive adults

• Anti-aging/autophagy: Modulates cell survival pathways and potentially enhances cellular cleanup mechanisms.

• Cancer support: Demonstrates apoptosis induction, reduced angiogenesis, and slowed proliferation in prostate cancer. Early human studies also show PSA improvements in men on androgen deprivation therapy.

8. Zinc Citrate

• Supports critical prostate functions: citrate production, apoptosis, cellular metabolism.

• Low zinc correlates with increased BPH risk; supplementation may help reduce or prevent prostate enlargement.

• Additionally, zinc supports immune function, cellular DNA preservation, and healthy aging.

Multidimensional Benefits of the Blend

Why This Synergistic Formulation Works Superbly

Synergy across pathways

• Hormone modulation: saw palmetto, nettle, centella, curcumin, zinc

• Immune & inflammatory reduction: botanicals and zinc

• Oxidative stress defence: polyphenol-rich extracts + curcumin

• Tissue growth regulation & apoptosis: pomegranate, grape seed, curcumin, zinc

• Smooth muscle support: saw palmetto, nettle

• Metabolic/cardiovascular benefits: curcumin, grape seed, pomegranate, zinc

Complementary health advantages

Combined, the formula supports urinary function, potentially slows prostate enlargement and PSA rise, offers metabolic improvements, and adds anti-aging resilience—covering many health priorities for men over 40.

Evidence-based

• Saw palmetto matches finasteride (common 5AR inhibitor) in symptom relief, with fewer side effects.

• Curcumin improves metabolic markers and blood pressure significantly.

• Polyphenols (pomegranate, grape seed) back apoptosis and PSA stabilization.

• Zinc maintains prostate and immune health while supporting testosterone balance.

Practical Guidance & Safety

• Formulation quality

• Medical oversight: Especially for men with prostate disease, metabolic conditions, or those on medication.

• Not a standalone cancer therapy: Supplements can complement but not replace medical care.

• Complement with lifestyle: Diet, exercise, stress management synergize strongly—especially for metabolic and prostate health.

Final Summary

This integrative blend offers a scientifically grounded, multi-pronged approach for:

• Relieving BPH symptoms & supporting urinary health,

• Providing adjunctive prostate cancer support,

• Improving metabolic & cardiovascular health,

• Slowing signs of aging and improving resilience.

When used judiciously—with medical consultation and quality standards—it can be a powerful asset in comprehensive men's health strategies. 

References & Research

• Cai T, et al. Herbal medicine and BPH management. Urology, 2015.
• McVary KT, et al. AUA guideline for BPH. Journal of Urology, 2011.
• Telles S, et al. Ganoderma lucidum and prostate health. Journal of Ethnopharmacology, 2018.