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Practitioner Formulated
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Fast Global Shipping
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Practitioner Formulated
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100% Secure Checkout
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Fast Global Shipping
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Practitioner Formulated
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100% Secure Checkout
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Fast Global Shipping
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Practitioner Formulated
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100% Secure Checkout
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Practitioner formulatedBy Jeff Butterworth N.D, 30 years in practice
Therapeutic dosesAmounts that match the research
International shippingWe ship worldwide
Real people, real supportTake the assessment and join the community
Why test
Most people have no idea where their nitric oxide sits.
By around 40, most adults make roughly half the nitric oxide they did at 20. The strips show you where you are. Ultimate 4 helps you move.
15 secSaliva test, at home, no needles.
2Nitric oxide pathways supported by Ultimate 4.
2 to 4 wksWhen most people see the strip colour deepen.
The proof loop
See it working.
1
Test your baselineFirst thing in the morning, before eating or brushing your teeth.
2
Take Ultimate 4 dailyOne scoop in water, morning or before exercise.
3
Retest weeklyTwo or three tests a week builds a clear picture.
4
Stay in rangeAim for the optimal deep-pink zone and keep it there.
What's in the box
Ultimate 4
The daily foundation
Both nitric oxide pathways plus antioxidant protection. 33 serves.
Nitric Oxide Test Strips
Your proof
Saliva strips with a colour chart. Results in about 15 seconds.
Don't guess. Test. It's the only way to know.
Jeff Butterworth N.DSpecialist Naturopath, 30 years in clinical practice
Jeff tests his own levels regularly and recommends starting with a baseline.
Ultimate Nitric Oxide BundleFrom $62.96 with Subscribe & Save
Customer Reviews
Overall rating: 4.9 / 5 from 62 reviews.
I love the Ultimate 4, its given me loads more energy, reduced inflammation in lower back with little to no back ache. Has improved circulation to my whole body
I am now on my 3rd order of Boost 3, ultimate 4 and the Testosterone TRx. I have noticeably more energy, less joint pain and I’m sleeping a lot better. I still get the occasional night sweat but it’s no longer every night. And my sleep score is now regularly above 90. I am 54 and hitting menopause.
Jeff’s Ultimate 4 and Boost have been game changers for my husband and I. We’ve been on them both for a month and our energy levels have gone through the roof! I’ve been dancing through the day like a little kid. No need for caffeine anymore 🙏😊
Only been using Ultimate 4 for 10 days now and I do feel like I have more energy. The test strips started off almost white but happy to say they are now registering slightly pink which means it’s working Woo Hoo 🙌
I knew Jeff designed good products because years ago I relied on 30 plus for women, so when I saw he had nitric oxide, I had to try it. I’ve been using it for two weeks and I certainly have more energy and sleep better, the arthritis in my knee has changed. I will keep using it
I am amazed at how quickly my energy increased. I have been having B12 shots every 3mths for years with no real benefit.
Ultimate 4 helped after only a few days and it tastes great.
Taste great , levels increased within a week & could definitely feel the increase in energy , almost too much energy after 2 weeks on it, so I reduced my dose to every 3rd day
Love the Boost 3 & Ultimate 4 mixed together, it’s so refreshing. I look forward to it every day. I’m yet to see noticeable results of the Trx yet, but it’s only been a few weeks.
I’ve tried plenty of supplements over the years, but this is honestly the best I’ve taken!
I took it to Europe with me & noticed a difference almost immediately. I had more energy, felt amazing & didn’t get sick once during the trip.
When I got home, I ran out while waiting for my next order. After five days without it, I could really notice the difference in how I felt. I’m back on it now & so impressed I’m getting the whole family started!
Cannot recommend it enough. Six stars if I could!
Taking the ultimate 4 and boost 3 and have never felt better. Loads of energy and i have had no coldsore outbreaks at all. Hubby 's blood pressure has improved and has also noticed more energy 100% recommend these products
My husband and I are 70 and 64 respectively and whilst we are still building our NO levels due to our age and other health factors we are thrilled to be experiencing a great improvement in our energy levels. No longer hitting a brick wall mid afternoon is just fantastic. We feel we are getting the opportunity to age better!
Love it - definitely feeling more energised. Cant seem to get a good reading on the nitric test strips but I do feel better. I think i may need to add the boost to complement on my next order
My name is Sheryl Ogston I am 75 years old, my daughter Rochelle gave me the ultimate 4 and boost 3 for my birthday, I have been talking it for a month now. I am feeling great, more energy, brain fog better, just feeling better all round and my nitric oxide levels are up to 110mg/L. I have been telling everyone I know to get onto it. Thanks Jeff for such great products.
So far one tub and energy more consistent. Took overseas whilst conquering the streets of Japan! Definitely needed! Purchased my second tub and will test more with this one to check NO levels
I noticed a difference in my energy levels & the flow on effect was my mood, within days of starting this. I can’t wait to see the long term effects it has.
2nd tub just started and enjoying the taste and easy of mixing the drink of a morning.
Starting to feel my energy increasing. Sleeping better and not needing to hit the snooze button on my alarm 😄
Following Jeff's recommendations with diet and exercise and looking forward to feeling fantastic again
Whilst it is too early to show an increase in my nitric oxide readings as I’ve only been taking this product for a few weeks, I definitely have more energy and improved brain function.
I was taking the women’s bundle for a month. Felt the benefits almost immediately. Unfortunately due to postage, my recent order got lost. I didn’t have anything for 3 weeks. Extremely disappointed, but I just had to be patient. My order finally arrived a few days ago and hands down, the best feeling! I actually think in hindsight the few weeks without these amazing products actually proved to me how good they really are. I Feel AMAZING! Thank you Jeff…. Long may this last🙏🏻
Clear, honest answers. Still unsure? Take the free assessment and join the community.
Place saliva on the pad, wait 10 to 20 seconds and compare with the colour chart. Deeper pink means higher nitric oxide. Test in the morning before eating or brushing.
Two to three times a week when you start, then weekly once you're in range.
Most people can, but if you take prescription medication or manage a health condition, check with your healthcare provider before starting a new supplement.
You save 10% on every order and it arrives monthly. You can skip, change or cancel any time from your account. No lock-in.
Once you've ordered, log in to your account to read The Butterworth Protocols as a flipbook or download the PDF. The Nitric Oxide Kitchen eating guide is emailed to you.
The bundle includes one unit of Ultimate 4, a daily oral powder formulated to support nitric oxide production, and one pack of Nitric Oxide Test Strips, a saliva-based at-home testing tool. Together they form a complete system for supporting and monitoring your cardiovascular health.
Testing and supplementing work best in combination. The test strips give you a baseline reading before you start, let you track whether your nitric oxide levels are responding, and help you see the difference your supplementation is making over time. Jeff recommends testing 2 to 3 times per week when starting out so you can see early changes as they happen.
Mix one scoop into water and drink daily. Ultimate 4 contains four ingredients: Arugula (Rocket) extract as the primary nitrate source, L-Citrulline which converts to L-Arginine to support nitric oxide synthesis, Ascorbic Acid (Vitamin C) to protect nitric oxide bioavailability, and Monk Fruit powder as a natural sweetener. One tub provides a 30 to 60 day supply.
Place a drop of saliva on the test pad and wait 10 to 20 seconds. Compare the resulting colour to the chart included in the pack. Deeper pink indicates higher nitric oxide levels. Testing first thing in the morning before eating or brushing your teeth gives the most accurate baseline reading. Note that foods high in nitrates, such as beetroot, spinach, and rocket, can temporarily raise readings. This is a normal part of how nitrate-rich diets work.
Most users notice changes within 30 days of consistent use. Using the test strips from the start means you can track your levels week by week rather than waiting to feel a difference. Blood pressure normalisation may require a GP to review and adjust any existing medication, so it is worth keeping your healthcare provider informed if that applies to you.
Yes. Both Ultimate 4 and the Nitric Oxide Test Strips are suitable for men and women. Nitric oxide plays the same fundamental role in circulation and cardiovascular health regardless of sex.
We recommend consulting your GP before starting if you are on any of these medications. Ultimate 4 is formulated to support healthy blood pressure and circulation, and as levels normalise your GP may need to review your medication doses. This is a positive outcome, but it does require medical oversight.
Yes. Ultimate 4 pairs particularly well with BOOST 3, which is also available as part of the Heart and Energy Bundle. All Butterworth Health products are designed to be used together and can be taken on the same morning routine.
Yes. A Subscribe and Save option is available at checkout. You can choose a 1 or 2 month delivery cycle and cancel, pause, or modify your subscription at any time. If you need help with your subscription, contact our support team directly.
Yes. All Butterworth Health products are vegetarian. Ultimate 4 is an oral powder with no animal-derived ingredients. The test strips are non-ingestible diagnostic tools.
We ship globally with capped shipping costs and priority dispatch. Orders ship the next business day. Most customers receive their order within 3 to 7 business days, though remote locations may take a little longer.
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