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Ultimate 4 Plus Nattokinase
Ultimate 4 + Nattokinase is an enhanced nitric oxide support formula that combines evidence-informed ingredients at therapeutic doses with nattokinase to promote healthy circulation and vascular function.
Nitric oxide is central to healthy blood flow, cardiovascular function, and delivery of oxygen and nutrients—processes that can decline with age. This updated formula supports nitric oxide production and preservation while adding nattokinase, a naturally derived enzyme that supports healthy fibrin balance and circulation. Jeff developed this product for himself and recommends it as a simple, reliable addition for those seeking improved circulation and long-term vitality.
We strongly suggest testing regularly to maintain healthy and optimal NO levels.
Healthy NO + nattokinase support may help with:
Supporting healthy cholesterol balance
Promoting normal blood pressure within a healthy range
Aiding cardiovascular health and circulation
Supporting healthy fibrin turnover and microcirculation (nattokinase)
Providing antioxidant defence and protecting cells from oxidative stress
Contributing to cognitive clarity and healthy brain circulation
Encouraging daily immune and antioxidant function
Assisting maintenance of healthy energy levels throughout the day
Improving exercise performance
Practitioner formulated
100% natural ingredients
Backed by real research
Therapeutic dosages
Decades of expertise
Be guided back to health
Ageing doesn't have to mean accepting less. Every Butterworth Health product is clinician-formulated to address the real physiological changes that happen after 40. declining hormones, reduced energy, slower recovery, and the quiet erosion of the vitality you once took for granted.
These aren't quick fixes. They're carefully considered formulas built to restore your body's natural rhythm, supporting hormonal balance, cardiovascular health, immune resilience, and sustained daily energy from the inside out. Evidence-based support, designed to work with your biology, not against it.
Ingredient
Amount
Nattokinase
20,000 FU
L-Citrulline
1620 mg
Beetroot Extract (20% nitrates)
1200 mg
Arugula Extract (10% nitrates)
1200 mg
Ascorbic Acid (Vitamin C)
600 mg
Glycine
600 mg
Taurine
360 mg
Hibiscus Extract
216 mg
Magnesium (from magnesium taurate)
180 mg
Silica
24 mg
Frequently Asked Questions
We've got clear, honest answers to help you make informed decisions. If you can't find what you're looking for, just reach out.
Ultimate 4 is formulated to support the body's natural nitric oxide production, a key molecule involved in healthy circulation and vascular function. It supports blood vessel flexibility and cardiovascular wellbeing, making it ideal for those focused on heart health or wanting to proactively support their circulatory system.
Most users experience no side effects when using this product as directed. It is well tolerated in general use. Speaking with your healthcare professional is recommended before use, particularly if you are currently under medical supervision.
If you are currently taking prescribed medications, we recommend discussing supplementation with your healthcare professional before starting. They can monitor your progress and advise on what is appropriate for your individual circumstances.
The formula contains Arugula extract, L-citrulline, Ascorbic Acid, and Monk Fruit powder. All ingredients are sourced from trusted suppliers with no artificial additives or fillers.
Use 1 scoop per day mixed into water. It combines well with BOOST. Most users notice benefits within 2–4 weeks of consistent use.
Yes. You can choose a subscription at checkout for automatic monthly delivery and save on each order for individual products, or choose specific combinations on either 1 month or 2 month cycles. You can cancel anytime or adjust your subscription easily. If you have any issues simply contact our support team directly.
Yes, all our products are vegetarian and the capsules are vegecaps.
This depends on the type of fast and your goal. Most people actually practice time-restricted eating rather than true fasting. Any food restriction under 24 hours is time-restricted eating. The benefits of fasting beyond 24 to 72 hours come from autophagy, and the products will break this process. Beyond 72 hours this effect is reduced and it is advisable to take the products to support the detoxification process. Under 24 hours you can take the products as normal.
We currently ship globally. Our goal is to build an international community of healthy and vital people. We have capped shipping costs to make it more affordable.
Most orders arrive within 3–7 business days, depending on location. Remote areas may take slightly longer.
Yes. You'll receive a tracking link by email once your order ships.
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Customer Reviews
Overall rating: 4.8 / 5 from 37 reviews.
Jeff’s Ultimate 4 and Boost have been game changers for my husband and I. We’ve been on them both for a month and our energy levels have gone through the roof! I’ve been dancing through the day like a little kid. No need for caffeine anymore 🙏😊
I knew Jeff designed good products because years ago I relied on 30 plus for women, so when I saw he had nitric oxide, I had to try it. I’ve been using it for two weeks and I certainly have more energy and sleep better, the arthritis in my knee has changed. I will keep using it
Only been using Ultimate 4 for 10 days now and I do feel like I have more energy. The test strips started off almost white but happy to say they are now registering slightly pink which means it’s working Woo Hoo 🙌
I am amazed at how quickly my energy increased. I have been having B12 shots every 3mths for years with no real benefit.
Ultimate 4 helped after only a few days and it tastes great.
Taste great , levels increased within a week & could definitely feel the increase in energy , almost too much energy after 2 weeks on it, so I reduced my dose to every 3rd day
Whilst it is too early to show an increase in my nitric oxide readings as I’ve only been taking this product for a few weeks, I definitely have more energy and improved brain function.
I was taking the women’s bundle for a month. Felt the benefits almost immediately. Unfortunately due to postage, my recent order got lost. I didn’t have anything for 3 weeks. Extremely disappointed, but I just had to be patient. My order finally arrived a few days ago and hands down, the best feeling! I actually think in hindsight the few weeks without these amazing products actually proved to me how good they really are. I Feel AMAZING! Thank you Jeff…. Long may this last🙏🏻
Loving this supplement. Can truly say this has had a noticeable effect with energy levels and overall feelings of wellness. So happy with this purchase. Thank you
I have only been taking it for two weeks but have seen a slight improvement in the testing stick level - in relation to energy I am yet to feel any difference but understand it may take a bit longer than two weeks to feel an increase
I have been taking these products for 4weeks now, and they taste delicious, however, I have not as yet, physically noticed any differences/benefits - but my levels are getting better each week when I test.
It’s been a few weeks now and I can say I feel different, like a cloud has been lifted, I move easier too. I go to sleep and don’t move, I wake up in the same position as I went to sleep.
Starting to sleep better, feeling like i have more energy and not having the afternoon slump so far happy with how it's gping and my NO levels have already increased since i started.
I have been taking this for a week now and feel I have more energy, getting better sleep and not still feeling tired when I wake up. I haven't tested my NO level yet but hoping it has improved.
i started by just doing 1 teaspoon for 2 weeks, was the lowest level on the strips, moved to 2 teaspoons 5 days ago and no second from bottom. have i felt any different? no. will keep doing til the product is done but im not feeling any different. cheers
Unfortunately the lid was not on the jar properly and the product dispersed through the postage sachel. I did email Butterworth Health with photos but did not receive a response . As for the product we have been using it for 4 days and our tests still indicate we are in rhe bottom level being low . We have a very clean healthy organic diet , do not use mouthwash or fluoride toothpaste . We will see how we go after a another week .
After a week and a half we have seen a change in NO readings. Will continue to monitor our progress. My husband’s first reading was 0 and mine was 10. Looking forward to improvements.
I have Chronic Dry Eye Syndrome and can confidently say the impact of this suite of products has started to change the quality of my acqueos tear film. Additionally I am sleeping better for the first time in so many years. I am keen to continue this regime and see what else continues to evolve in my health journey. Try this product you won't be disappointed!!!!
